Fig. 4: Genetic correlations between BAG and a wide range of complex traits. | Nature Aging

Fig. 4: Genetic correlations between BAG and a wide range of complex traits.

From: Genome-wide analysis of brain age identifies 59 associated loci and unveils relationships with mental and physical health

Fig. 4

a, Genetic correlation matrix between BAG (columns) and 38 selected phenotypes from different health domains (rows). *P < 0.05 (nominal significance). **FDR < 0.05 (level of significance after correction for multiple testing). b, Volcano plot showing the magnitude (x axis) and significance (y axis) of LDSC-based genetic correlations between GM BAG and 989 traits, whose summary statistics were provided in ref. 80. The dashed horizontal line indicates the FDR-adjusted level of significance. All P values are two-sided. c, Forest plot showing the genetic correlation coefficients and standard errors for a subset of 23 exemplary traits that showed significant genetic correlations with GM BAG.

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