Fig. 5: Genetic effect-size distribution analysis of BAG. | Nature Aging

Fig. 5: Genetic effect-size distribution analysis of BAG.

From: Genome-wide analysis of brain age identifies 59 associated loci and unveils relationships with mental and physical health

Fig. 5

a, Results are shown for combined GM and WM BAG, with neuroticism and standing height included as reference traits; effect-size distributions of the underlying susceptibility variants are shown; wider tails indicate a greater proportion of large-effect variants. b, Predicted number of genome-wide significant loci as a function of sample size. c, Proportion of genetic variance explained by genome-wide significant loci as a function of sample size.

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