Fig. 1: Representation of cellular tissues in SimuCell3D.
From: SimuCell3D: three-dimensional simulation of tissue mechanics with cell polarization
a Schematics of the features that cell-based models must possess to be applicable to a broad range of morphogenetic problems. b, Representation of cell membranes as closed triangulated surfaces with non-uniform material properties on the basis of cell polarity (colors). c, Summary of different forces acting on the triangulated cell membranes. d, Illustration of cell division perpendicular to a division plane (purple). e, Computational efficiency of different 3D cell-based models in an exponential-growth scenario. The dashed black line is a fitted power law \(T=a{N}_{{{{\rm{c}}}}}^{\alpha }\) with coefficients a = 0.013 s and α = 1.33. f, Illustration of different tissue topologies and intra- or extracellular features that can be simulated with SimuCell3D. All surfaces can be non-convex.
