Fig. 5: Phasing structural variants on subgenomic RNA (sgRNA) derived full-length (FL) transcript units (TUs) reveals SARS-CoV-2 proteome complexity. | Communications Medicine

Fig. 5: Phasing structural variants on subgenomic RNA (sgRNA) derived full-length (FL) transcript units (TUs) reveals SARS-CoV-2 proteome complexity.

From: Reduced subgenomic RNA expression is a molecular indicator of asymptomatic SARS-CoV-2 infection

Fig. 5

a An example of four deletions co-occurred on a sgRNA_ORF3a molecule uncovered by FL iso-seq analysis. b Examples show identical deletions (highlighted in boxes) detected in multiple FL cDNAs encoding different sgRNA species. c Distribution of predicted wild-type and mutant proteins encoded from the sgRNA-derived FL TUs.

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