Fig. 3: Percentage of change in chest-patch indicators for participants who reported at least one local or systemic reaction and those who reported no reaction during the daytime and the nighttime.

Percentage of change in chest-patch indicators for participants who reported at least one local or systemic reaction (symptomatic, \(n=80\) participants) and those who reported no reaction (asymptomatic, \(n=55\) participants) during the daytime and the nighttime: a skin temperature, b heart rate, c cardiac output, and d respiratory rate. Error bars represent 90% confidence intervals. Horizontal dashed lines represent no change compared to the levels observed on the day prior to vaccination. Significant differences compared to the measurements levels observed on the day prior to vaccination at a 0.05 level are marked with *. Significant differences between symptomatic and asymptomatic participants at a 0.05 level are marked with #.