Table 2 Assay performance: calculation of the sensitivities with sera from convalescent donors and specificities based on the individual assay performances in A.

From: German federal-state-wide seroprevalence study of 1st SARS-CoV-2 pandemic wave shows importance of long-term antibody test performance

Convalescent donors

Potentially cross-reactive sera

 

EI-IgG

Abbott-IgG

Roche-Ig

 

EI-IgG

Abbott-IgG

Roche-Ig

n

61

61

61

n

128

78

122

Positive

52

49

55

Crossreaction

2

4

0

% Negative

14.75

19.67

9.84

%

1.67

1.69

0

Sensitivity (%)

85.25

80.33

90.16

Specificity (%)

98.33

98.31

100

CI (%)

73.83;  93.02

68.16; 89.04

79.81; 96.30

CI (%)

94.47; 99.81

87.39; 98.59

97.02; 100.00

  1. Euroimmun-IgG = EI-IgG. 95% confidence intervals (CI %) were calculated according to Clopper and Pearson34.