Table 1 Baseline characteristics of the ASCVD study cohort by the presence or absence of a statin prescription.

From: Using deep learning-based natural language processing to identify reasons for statin nonuse in patients with atherosclerotic cardiovascular disease

Characteristic at index date (N [% by column] unless otherwise noted; N = 56, 530)

Statin prescription present (N = 34,234)

Statin prescription absent (N = 22,296)

p value

Age (years, mean ±SD)

68.6 ± 11.6

65.5 ± 14.7

<0.001

Female

12179 (35.6%)

10054 (45.1%)

<0.001

Race

Non-Hispanic White

19086 (55.7%)

13031 (58.4%)

<0.001

Non-Hispanic Black

1687 (4.9%)

1297 (5.8%%)

Hispanic

3167 (9.3%)

2139 (9.6%)

Non-Hispanic Asian

5553 (16.2%)

3028 (13.6%)

Other

3123 (9.1%)

1656 (7.4%)

Provider location

SHC

20442 (59.7%)

11152 (50.0%)

<0.001

UHA

12226 (35.7%)

9779 (43.9%)

ValleyCare

1552 (4.5%)

1191 (5.3%)

ASCVD type

Coronary artery

20152 (58.9)

7577 (34.0%)

<0.001

Cerebrovascular

7155 (20.9)

5484 (24.6%)

Peripheral Arterial

3117 (9.1)

3072 (13.8%)

Polyvascular

3810 (11.1%)

6163 (27.6%)

Current smoking

2006 (5.9%)

925 (4.1%)

<0.001

Hospitalizations in prior 1 year (N)

3000 (8.8%)

1831 (8.2%)

0.022

Insurance status

Private

6984 (20.4%)

5420 (24.3%)

<0.001

Medicare

20097 (58.7%)

11696 (52.4%)

Medicaid

2144 (6.3%)

1529 (6.8%)

PCSK9 inhibitors

59 (0.2%)

68 (0.3%)

0.001

Ezetimibe

1697 (5.0%)

292 (1.3%)

<0.001

Total cholesterol (mg/dL, mean ± SD)

167.2 ± 46.2

169.3 ± 39.8

0.698

LDL-cholesterol level at index (mg/dl, mean ± SD)

90.2 ± 38.3

107.9 ± 37.2

<0.001

Chronic kidney disease

5286 (15.4%)

2248 (10.0%)

<0.001

Heart failure

6091 (17.8%)

2937 (13.2%)

<0.001

Atrial fibrillation

5565 (16.3%)

3393 (15.2%)

0.003

Liver disease

1966 (5.7%)

1483 (6.7%)

<0.001

Creatine kinase level (mean ± SD)

252.3 ± 746.6

386.5 ± 1022

0.001

Encounter specialties

Cardiology

10906 (31.8%)

7985 (35.8%)

<0.001

Internal medicine

3176 (9.2%)

1816 (8.1%)

Family medicine

2263 (6.6%)

991 (4.4%)

Vascular surgery

1486 (4.3%)

1093 (4.9%)

Radiology

1181 (3.5%)

993 (4.4%)

Neurosurgery

664 (1.9%)

1017 (4.6%)

Primary care

1106 (3.2%)

459 (2.0%)

Emergency medicine

977 (2.8%)

540 (2.4%)

Neurology

802 (2.3%)

618 (2.8%)

Anesthesiology

791 (2.3%)

510 (2.3%)

Others

10882 (31.8%)

6274 (28.1%)

  1. ASCVD atherosclerotic cardiovascular disease, LDL low-density lipoprotein, SHC Stanford Health Care (academic hospital), UHA University Health Alliance (community practice network), ValleyCare ValleyCare Hospital (community hospital), SD standard deviation.