Fig. 2: In silico prediction and comparison of strong-, weak- and no-binding peptides derived from the ancestral Wuhan and B.1.1.529 Spike proteins.
From: Vaccines against the original strain of SARS-CoV-2 provide T cell memory to the B.1.1.529 variant
a The X-axis indicates the potential conversions of non-binding (NB), weak binding (WB) or strong binding (SB) 9-mer peptides and the Y-axis indicates the most common DRB1 alleles in the European-Caucasian population. b Corresponding analysis to (a) highlighting the most common HLA-I alleles in the European-Caucasian population on the Y-axis. The numbers and the color code indicate the number of 9-mer peptides with predicted in silico conversions in B.1.1.529 compared to the ancestral Wuhan strain for the respective HLA allotype. Red: low conversion rate; Green: high conversion rate.
