Fig. 2: Perinatal outcomes of women living with HIV receiving different ARV regimens, compared to HIV-negative women.

Results of random-effects meta-analyses to estimate attributable risk of perinatal outcomes associated with women living with HIV (WLHIV) receiving no ARVs (a), monotherapy (b) or cART initiated antenatally (c) and preconception (d), compared to HIV-negative women. Attributable risks, 95% confidence intervals and numbers of studies and women included in the analysis of each perinatal outcome for each comparison are displayed. Forest plots of meta-analyses can be found in Supplementary Figs. 1–24. Statistically significant results are presented with red dots and non-significant results with black dots. AR Attributable risk, ARVs Antiretroviral drugs, cART Combination antiretroviral therapy, CI Confidence interval, LBW Low birth weight, NND Neonatal death, PTB Preterm birth, SGA Small for gestational age, VPTB Very PTB, VLBW Very LBW, VSGA Very SGA, WLHIV Women living with HIV.