Fig. 2: Significant MR results for the causal relationship between TRS and biomarkers.

The error bars indicate 95% confidence intervals (CIs). An asterisk (*) indicates the presence of pleiotropy in this MR analysis, which results in more precise estimates from MR-Egger. A hashtag (#) indicates the presence of heterogeneity in this MR analysis, which results in more precise estimates from the weighted median. TRS treatment-resistant schizophrenia, IVW inverse variance weighted, WM weighted median, MR Mendelian randomization.