Fig. 4: CO2 response for varying levels of Fentanyl bolus dose. | Communications Medicine

Fig. 4: CO2 response for varying levels of Fentanyl bolus dose.

From: Whole body physiology model to simulate respiratory depression of fentanyl and associated naloxone reversal

Fig. 4

a Total pulmonary ventilation, b oxygen partial pressure for a single 0.5 mg bolus dose of fentanyl. Subfigure c displays the CO2 response, computed for varying levels of steady-state fentanyl concentrations. Respiratory depression as a function of the fentanyl administration tracks well with the experimental data from50. Error bars represent one standard deviation from the mean of the data.

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