Table 5 Additional potential pathogens detected

From: Unified metagenomic method for rapid detection of microorganisms in clinical samples

Sample number

Sample type

Routine testing detections

Sequencing results after 2 h

Microorganisms (Ct values)

Number of microbial reads

Percentage of bacterial reads

51

BAL

Agar culture negative S. pneumoniae urine Ag positive

S. pneumoniae

13

26.531

11

Sputum

Commensals

R. mucilaginosa

S. mitis

S. pneumoniae

S. oralis

SARSCov2 (Ct 20)

P. histicola

29765

1014

835

549

413

395

87.446

2.979

2.453

1.613

N/A

1.16

20

BAL

Agar culture negative

S. pneumoniae urine Ag positive

PIV3

S. pneumoniae

Parainfluenza virus 3 (Ct 31)

985

30

91.628

N/A

34

BAL

P. aeruginosa

PCR not requested

P. aeruginosa

Rhinovirus A (Ct 24)

52007

56

67.401

N/A

36

Sputum

Commensals

E. corrodens

N. mucosa

V. parvula

R. mucilaginosa

P. melaninogenica

P. jejuni

N. meningitidis

N. cinerea

E. coli

K. denitrificans

A. defectiva

Influenza virus A (Ct 24)

195

164

39

37

31

21

20

13

12

7

7

2

32.939

27.703

6.588

6.25

5.236

3.547

3.378

2.196

2.027

1.182

1.182

N/A

37

Sputum

C. freundii

C. freundii

Human

gammaherpesvirus 4

Rhinovirus B (Ct25)

5660

44

15

70.119

N/A

N/A

49

BAL

P. aeruginosa

PCR not requested

P. aeruginosa

SARSCov2 (Ct 19/21)

12016

3935

66.67

N/A

50

NTS

Negative

Influenza virus C

40

N/A

  1. H high growth, L light growth, S scanty growth.