Fig. 2: The Diet-microbiota subgroup: heatmap of the relationship between dietary measures, microbial taxa, and disease status. | Communications Medicine

Fig. 2: The Diet-microbiota subgroup: heatmap of the relationship between dietary measures, microbial taxa, and disease status.

From: Mediterranean diet and associations with the gut microbiota and pediatric-onset multiple sclerosis using trivariate analysis

Fig. 2

MS multiple sclerosis, aMED alternate Mediterranean diet score, P&R meat processed and red meat, MUFA:SFA ratio of monounsaturated to saturated fat, sp. unknown species. a displays the 7 genera and b displays the 12 ASVs that were significantly associated with MS (P < 0.050). The association of each dietary measure Z-score with taxa relative abundance (the outcome variable) was represented as beta coefficients. The association of each taxa Z-score with disease status (n = 27 MS cases vs n = 32 controls, the outcome variable in this case) was represented as log odds ratios (far most right column). All results were adjusted for library size, Bristol Stool Scale group, age (in years) at the food frequency questionnaire completion and sex while beta coefficients were also adjusted for total energy intake. Dietary measures and taxa were standardized to Z-scores only when modeled as an independent variable. Actual estimates and associated P and Q values are available in Supplementary Table. Heatmap was created using the R package pheatmap (v. 1.0.12). Source data are provided as a Source Data File.

Back to article page