Fig. 2: Overlapping associations reveal distinct trends for different biomarker groups in ME/CFS and comorbid conditions.

Forest plots compare the odds ratios and 95% confidence intervals shown per 1-SD increment for a selection of biomarkers in ME/CFS (red), hypertension (light blue), depression (lavender), asthma (brown), IBS (green), hay fever (salmon) hypothyroidism (blue) and migraine (purple). All models were adjusted for gender, age, cholesterol lowering medication, and fish oil supplements. Filled points indicate statistically significant associations at P < 6.25\(\times\)10−3 (Bonferroni threshold with trait-wise adjustment), and hollow points are non-significant. See Supplementary Fig. 6 for forest plots of the complete biomarker set.