Fig. 4: Inverse relationship between plasma lipid changes with MMKD intervention and signatures associated with Alzheimer’s disease. | Communications Medicine

Fig. 4: Inverse relationship between plasma lipid changes with MMKD intervention and signatures associated with Alzheimer’s disease.

From: Consuming a modified Mediterranean ketogenic diet reverses the peripheral lipid signature of Alzheimer’s disease in humans

Fig. 4

A scatter plot correlating lipid class associations with MMKD intervention and Alzheimer’s disease (data previously reported Huynh et al. 2020). a Lipid classes nominally associated with both MMKD and prevalent/existing AD (highlighted in blue, class totals, meta-analysis of both AIBL and ADNI) and b Lipid classes nominally associated with both MMKD and incident/future risk of AD (highlighted in red). Exact p-values and coefficients are in Supplementary Data 6. AD: Alzheimer’s Disease, Hex2Cer: Dihexosylceramide, Hex3Cer: Trihexosylceramide, LPE: Lysophosphatidylethanolamine, MMKD: Modified Mediterranean-Ketogenic Diet, NL: Neutral Loss, PC: Phosphatidylcholine, PE: Phosphatidylethanolamine, SHexCer: Sulfatide, TG: Triglyceride.

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