Fig. 7: Subgroup analysis of various influencing factors on Infarct Size following ECM treatment. | Communications Medicine

Fig. 7: Subgroup analysis of various influencing factors on Infarct Size following ECM treatment.

From: Preclinical extracellular matrix-based treatment strategies for myocardial infarction: a systematic review and meta-analysis

Fig. 7

a Subgroup analysis showing pooled estimates (black symbols) per stratum for the variables species, sex, ECM source, method of ECM administration and timing of ECM treatment [Early (< 1day post-MI), Mid (= 1–7days post-MI), Late (>7days post-MI)]. The overall pooled mean difference (MD) from a random effects model, is shown by a red dotted line and a diamond (respectively). Error bars represent 95% confidence interval (CI). N represents the number of experiments within each subgroup. Meta-regression for timing of outcome measurement (b) and ECM dose (c). NR not reported, ECM extracellular matrix, dECM decellularized extracellular matrix.

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