Fig. 2: Distribution of the sum of participants’ responses to two measures of symptom severity—physical and social effects—measured before vaccination and surveys sent 2, 6, and 12 weeks after vaccination.

To measure physical effect of each symptom from a list of 125 symptoms, participants were asked, “While experiencing these symptoms, how much do/did they bother you in terms of discomfort or pain?” Similarly, to measure social effects, participants were asked, “After quarantine, how much does/did the symptom impair your social or family functioning compared to pre-COVID? Responses for each symptom were scored 0–4 (Supplementary Table 1) and summed for each participant. Boxplots show the distribution of responses, with points indicating the score for each participant; the central lines indicate the group median values, the top and bottom lines indicate the 75th and 25th percentiles, respectively, the whiskers represent 1.5× the interquartile range. Higher values suggest a greater symptom burden, and a value of 0 suggests no symptom burden Data missing for n = 2 at 2 weeks and n = 2 at 6 weeks.