Fig. 4: Clusterization of patients based on factors and phenotypes. | Communications Medicine

Fig. 4: Clusterization of patients based on factors and phenotypes.

From: A multi-omics integration approach relying on circulating factors does not discern subtypes of childhood type 1 diabetes

Fig. 4

Phenotypes include age, sex, family history of T1D (T1D relative), genetic predisposition (GRS-2), percentile of BMI (BMIp), presence of diabetic ketoacidosis (DKA), neutrophil count, C-peptide levels, disease outcome measured by the 12-month follow-up lower insulin- dose adjusted A1c (IDAA1c) and proinsulin/C-peptide ratio (PI/C-pep). White squares indicate that the phenotypic trait is not available for that patient. The legend shows cut-off values used to discriminate patient groups. Each variable is represented with a binary color scale: red tones indicate values equal to or lower than the reference threshold, while green tones highlight those higher.

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