Table 1 Characteristics of the cohort of pediatric new-onset T1D patients

From: A multi-omics integration approach relying on circulating factors does not discern subtypes of childhood type 1 diabetes

Age, median (IQR)

11.46 (9.38–13.94)

n = 146

Sex, F (%)

54 (36.99)

n = 146

Presence of T1D relatives, n (%)

32 (22.54)

n = 142

GRS-2, median (IQR)

14.42 (13.16–16.07)

n = 90

BMIp, median (IQR)

36.00 (6.78–73.60)

n = 144

Presence of DKA, n (%)

45 (30.82)

n = 146

HbA1c (mmol/mol), median (IQR)

105.00 (88.75–119.00)

n = 146

C-peptide (ng/ml), median (IQR)

0.45 (0.28–0.72)

n = 146

Anti-tTG, n (%)

20 (13.70)

n = 146

Anti-TPO, n (%)

19 (13.01)

n = 146

Neutrophil count (10^9/L), median (IQR)

2.30 (1.80–2.70)

n = 138

Number of AAb:

 

n = 145

 1, n (%)

21 (14.48)

 

 2, n (%)

47 (32.41)

 

 3, n (%)

54 (37.24)

 

 4, n (%)

23 (15.86)

 

Type of AAb:

 

n = 145

 GADA, n (%)

125 (86.21)

 

 IA-2A, n (%)

99 (68.28)

 

 IAA, n (%)

38 (26.21)

 

 ZnT8A, n (%)

107 (73.79)

 

IDAA1c ≤ 9, n (%)

41 (35.65)

n = 115

  1. GRS-2 T1D-Genetic Risk Score-2, BMIp percentile of body mass index, DKA diabetic ketoacidosis, AAb autoantibodies, anti-TPO anti-thyroid peroxidase antibody, anti-tTG IgA anti-tissue transglutaminase antibodies, IDAA1c insulin- dose adjusted A1c, IQR interquartile range.
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