Fig. 4: Interventions associated with increased cardiac glucose oxidation. | Communications Medicine

Fig. 4: Interventions associated with increased cardiac glucose oxidation.

From: Modulation of cardiac fatty acid or glucose oxidation to treat heart failure in preclinical models: a systematic review and meta-analysis

Fig. 4

Data are presented as Hedges’ g, which is calculated using a multivariate meta-analysis to enclose all measures of heart function reported in each study. Bars represent 95% CI. Tests for the overall effect and confidence intervals are based on the Knapp and Hartung method. Individual box sizes are determined by their weight in the meta-analysis model. Number of control (n = 393) and intervention group (n = 418) animals. The components of heterogeneity across levels are quantified by partitioned I2-statistics: (2) between-outcomes; (3) between-interventions; (4) between studies. IR ischemia-reperfusion, PO pressure overload, DMC diabetic cardiomyopathy, Pacing pacing-induced heart failure.

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