Fig. 1: CCC study sample collection and vaccination timepoints, SARS-CoV-2 cases in Catalonia, and main SARS-CoV-2 lineages circulating in Spain over the study period.
From: Determinants of antibody levels and protection against omicron BQ.1/XBB breakthrough infection

The grey plot represents the number of SARS-CoV-2 cases at a given time in Catalonia according to the official data available from IDESCAT (Statistical Institute of Catalonia, https://www.idescat.cat/dades/covid19/?lang=es (accessed on 03 July 2024)). The bottom timeline depicts the main SARS-CoV-2 lineages circulating in Spain at those time intervals according to GISAID. The orange lines represent the three follow-up periods (6 months each) for breakthrough infections in this study. The top grey lines represent the cohort of participants recruited during the first wave of the COVID-19 pandemic (March–April 2020, n = 247) with symptomatic SARS-CoV-2 infection confirmed by rRT-PCR and/or RDT (first-infected), and the cohort recruited in March–April 2021 after completing full primary vaccination (n = 200) without evidence of prior infection (first-vaccinated). T: Timepoint.