Fig. 3: In silico analysis of TPA sequences containing the 1873G variant at the TP0705 locus responsible for partial resistance to the tested antibiotics. | Communications Medicine

Fig. 3: In silico analysis of TPA sequences containing the 1873G variant at the TP0705 locus responsible for partial resistance to the tested antibiotics.

From: Resistance to ceftriaxone and penicillin G among contemporary syphilis strains confirmed by natural in vitro mutagenesis

Fig. 3

Data were taken from the PubMLST database14 and included 1408 isolates. Allele 10 is considered the reference allele since it was found in both reference TPA strains- Nichols and SS14. Allele 1 is the most common among contemporary SS14-like strains. *Among the rare 1873G alleles, alleles 4 and 6 (n = 2 isolates) were omitted from the analysis due to the absence of SS14/Nichols clade classification.

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