Fig. 5: Comparison of im.CTC and WBC proteomic profiles.

a UMAP projection constructed from immune marker expression profiles of gated WBC populations and im.CTCs. b Distributions of cancer and immune marker expression across WBCs compared to im.CTCs. Ion counts are displayed with arcsinh-transformed x-axes. Colors correspond to cell types from the legend in (a). c Scatter plot of CD45RO versus CD45RA expression in im.CTCs, indicated as green dots. The density plot in the background was generated from the CD3 + T-cell population for comparison. Ion counts are displayed with arcsinh-transformed axes.