Fig. 3: Replicon types and antimicrobial resistance (AMR) gene carriage of the global dataset of plasmids carrying mcr-9 and mcr-10 (n = 326).

a Comparison of plasmid sizes grouped according to incompatibility replicon types. Colored dots represent the mcr alleles present in the plasmids. Black diamonds show group means and black error bars show the 95% confidence intervals. b Comparison of the number of AMR genes detected in each plasmid grouped according to incompatibility replicon types. Only replicon groups represented by three or more genomes are shown for visual clarity. White diamonds show group means and white error bars show the 95% confidence intervals. c Comparison of the number of AMR genes present in genomes of multi-replicon and single-replicon plasmids. Black dots represent individual plasmids. For the box plots in (A, C), the box represents the interquartile range, horizontal line in the middle of the box represents the median, and whiskers represent the minimum and maximum values. Details on the global plasmids and replicon groups are presented in Supplementary Data 3 and 6.