Fig. 7: Identification and characterization of aging-associated proteins (AARPs and DARPs) via intersection analysis. | Communications Medicine

Fig. 7: Identification and characterization of aging-associated proteins (AARPs and DARPs) via intersection analysis.

From: Decoding sexually dimorphic proteomic landscapes in the context of aging and mortality

Fig. 7

a Venn diagrams showing the AARPs in females. b PPI network of AARPs in females (the top 20 proteins with the highest degree). The size of each node represents the degree of connectivity of the corresponding protein in the PPI network, with larger nodes indicating higher connectivity. c Venn diagrams showing the DARPs in females. d PPI network of DARPs in females. The size of each node represents the degree of connectivity of the corresponding protein in the PPI network, with larger nodes indicating higher connectivity. e Venn diagrams showing the AARPs in males. f PPI network of AARPs in males (the top 20 proteins with the highest degree). The size of each node represents the degree of connectivity of the corresponding protein in the PPI network, with larger nodes indicating higher connectivity. g Venn diagrams showing the DARPs in males. h PPI network of DARPs in males (the top 20 proteins with the highest degree). The size of each node represents the degree of connectivity of the corresponding protein in the PPI network, with larger nodes indicating higher connectivity. i Venn diagrams showing the overlapping AARPs in females and males. j PPI network of AARPs in females and males (the top 20 proteins with the highest degree). The size of each node represents the degree of connectivity of the corresponding protein in the PPI network, with larger nodes indicating higher connectivity. k Venn diagrams showing the overlapping DARPs in females and males. l PPI network of DARPs in females and males. The size of each node represents the degree of connectivity of the corresponding protein in the PPI network, with larger nodes indicating higher connectivity. Bar plots depicting the results of the GO (m) and KEGG (n) enrichment analysis of AARPs in both females and males.

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