Fig. 4: Group-level SBC analysis results.
From: Shared neurobiological changes in individuals with Crohn’s disease and major depressive disorder
Group-level SBC analysis results showing a 3D glass-brain visualization of clusters identified via GLM analysis (top row within subplots) and boxplots displaying mean Fisher Z-transformed connectivity values within these clusters, stratified by group (n = 13 per group) (bottom row within subplots). Individual data points are overlaid on boxplots to illustrate within-group variability. Whole-brain SBC maps were generated using seed regions defined by the entire significant cluster regions identified in the fALFF group comparison analysis. Differences in connectivity are shown for a the HC group versus the MDD group (HC > MDD), b the HC group versus the CD group (HC > CD), c the HC group compared to a combined average of the MDD and CD groups (HC > 0.5MDD + 0.5CD), and d regions with altered connectivity between the MDD and CD groups (MDD > CD). Clusters are shown in the left and right medial views of the glass brain.
