Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Review Article
  • Published:

Mental health and treatment challenges in older adults

Abstract

Stereotypical views of ageing and about older adults can be barriers to older adults receiving psychological interventions for common mental health conditions. Such negative age stereotypes in some health professionals and older adults themselves might reduce expectations for change and improvement as a result of psychotherapy. In this Review, we discuss contemporary psycho-gerontological research about ageing experiences and explore the utility of this research for working with older adults with depression and anxiety disorders. We outline health-related and psychological processes that are common in older adults and briefly review the evidence for the range of psychotherapies suitable for use with this population. Innovations in the application of psychological therapies with older adults demonstrate the scope for interventions to substantially improve quality of life and empower people to age well. These innovations also enhance understanding of how best to support people living with dementia and their caregivers. Finally, we provide recommendations aimed at improving psychotherapy treatment outcomes and for future research on the psychological care of older adults.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Comprehensive cognitive formulation for cognitive behavioural therapy with older adults.
Fig. 2: Case example of a completed timeline.

Similar content being viewed by others

References

  1. United Nations Department of Economic and Social Affairs. World population prospects 2022: summary of results. https://www.un.org/development/desa/pd/content/World-Population-Prospects-2022 (2022).

  2. National life tables — life expectancy in the UK: 2021 to 2023. Office for National Statistics https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/lifeexpectancies/bulletins/nationallifetablesunitedkingdom/2021to2023additionaldata (2025).

  3. Robine, J.-M. Ageing populations: we are living longer lives, but are we healthier? United Nations, Department of Economics and Social Affairs, Population Division https://desapublications.un.org/working-papers/ageing-populations-we-are-living-longer-lives-are-we-healthier (2021).

  4. Vaupel, J. W., Villavicencio, F. & Bergeron-Boucher, M.-P. Demographic perspectives on the rise of longevity. Proc. Natl Acad. Sci. 118, e2019536118 (2021).

    Article  PubMed  PubMed Central  Google Scholar 

  5. Fries, J. F., Bruce, B. & Chakravarty, E. Compression of morbidity 1980–2011: a focused review of paradigms and progress. J. Aging Res. 2011, 261702 (2011).

    Article  PubMed  PubMed Central  Google Scholar 

  6. Scott, A. J. The longevity society. Lancet Healthy Longev. 2, e820–e827 (2021).

    Article  PubMed  Google Scholar 

  7. Guidelines for psychological practice with older adults. https://www.apa.org/practice/guidelines/older-adultsAmerican Psychological Association (2024).

  8. Koder, D., Bhar, S., Silver, M. & Stargatt, J. Effects of clinical placements in residential aged care settings on geropsychology competencies among provisional psychologists in Australia. Aust. Psychol. https://doi.org/10.1080/00050067.2025.2501639 (2025).

  9. Hinrichsen, G. A., Emery-Tiburcio, E. E., Gooblar, J. & Molinari, V. A. Building foundational knowledge competencies in professional geropsychology: Council of Professional Geropsychology Training Programs (CoPGTP) recommendations. Clin. Psychol. Sci. Pract. 25, e12236 (2018).

    Article  Google Scholar 

  10. Plotkin, D. A. Older adults and psychoanalytic treatment: it’s about time. Psychodyn. Psychiatry 42, 23–50 (2014).

    Article  PubMed  Google Scholar 

  11. Carstensen, L. L. Socioemotional selectivity theory: the role of perceived endings in human motivation. Gerontologist 61, 1188–1196 (2021).

    Article  PubMed  PubMed Central  Google Scholar 

  12. Sims, T., Hogan, C. L. & Carstensen, L. L. Selectivity as an emotion regulation strategy: lessons from older adults. Curr. Opin. Psychol. 3, 80–84 (2015).

    Article  PubMed  PubMed Central  Google Scholar 

  13. Haigh, E. A. P., Bogucki, O. E., Sigmon, S. T. & Blazer, D. G. Depression among older adults: a 20-year update on five common myths and misconceptions. Am. J. Geriat. Psychiatry 26, 107–122 (2018).

    Article  Google Scholar 

  14. Kok, R. M. & Reynolds, C. F. 3rd Management of depression in older adults: a review. JAMA 317, 2114–2122 (2017).

    Article  PubMed  Google Scholar 

  15. Amare, A. T. et al. The prevalence, trends and determinants of mental health disorders in older Australians living in permanent residential aged care: implications for policy and quality of aged care services. Aust. NZ J. Psychiatry https://doi.org/10.1177/0004867420945367 (2020).

  16. Wang, J. et al. Prevalence of depression and depressive symptoms among outpatients: a systematic review and meta-analysis. BMJ Open 7, e017173 (2017).

    Article  PubMed  PubMed Central  Google Scholar 

  17. Lamont, R. A., Swift, H. J. & Abrams, D. A review and meta-analysis of age-based stereotype threat: negative stereotypes, not facts, do the damage. Psychol. Aging 30, 180–193 (2015).

    Article  PubMed  PubMed Central  Google Scholar 

  18. Blanchflower, D. G., Bryson, A. & Xu, X. The declining mental health of the young and the global disappearance of the hump shape in age in unhappiness. PLoS ONE https://doi.org/10.1371/journal.pone.0327858 (2024).

  19. Blanchflower, D. G. Is happiness U-shaped everywhere? Age and subjective well-being in 145 countries. J. Popul. Econ. 34, 575–624 (2021).

    Article  PubMed  Google Scholar 

  20. Mather, M. & Carstensen, L. L. Aging and motivated cognition: the positivity effect in attention and memory. Trends Cogn. Sci. 9, 496–502 (2005).

    Article  PubMed  Google Scholar 

  21. Carstensen, L. L. & DeLiema, M. The positivity effect: a negativity bias in youth fades with age. Curr. Opin. Behav. Sci. 19, 7–12 (2018).

    Article  PubMed  Google Scholar 

  22. Diehl, M., Smyer, M. A. & Mehrotra, C. M. Optimizing aging: a call for a new narrative. Am. Psychol. 75, 577–589 (2020).

    Article  PubMed  PubMed Central  Google Scholar 

  23. Heckhausen, J. et al. Goal changes and healthy aging. 76, S105–S114 (2021).

  24. Heckhausen, J., Wrosch, C. & Schulz, R. Agency and motivation in adulthood and old age. Annu. Rev. Psychol. 70, 191–217 (2019).

    Article  PubMed  Google Scholar 

  25. Ardelt, M. Empirical assessment of a three-dimensional wisdom scale. Res. Aging 25, 275–324 (2003).

    Article  Google Scholar 

  26. Baltes, P. B. & Staudinger, U. M. Wisdom. A metaheuristic (pragmatic) to orchestrate mind and virtue toward excellence. Am. Psychol. 55, 122–136 (2000).

    Article  PubMed  Google Scholar 

  27. Glück, J. Wisdom and aging. Curr. Opin. Psychol. 55, 101742 (2024).

    Article  PubMed  Google Scholar 

  28. Weststrate, N. M. & Glück, J. Hard-earned wisdom: exploratory processing of difficult life experience is positively associated with wisdom. Dev. Psychol. 53, 800–814 (2017).

    Article  PubMed  PubMed Central  Google Scholar 

  29. Freund, A. Successful aging as management of resources: the role of selection, optimization, and compensation. Res. Hum. Dev. 5, 94–106. (2008).

    Article  Google Scholar 

  30. Baltes, P. B. & Baltes, M. M. Successful Aging: Perspectives from the Behavioral Sciences (Cambridge Univ. Press, 1990).

  31. Freund, A. M. Successful aging as management of resources: the role of selection, optimization, and compensation. Res. Hum. Dev. 5, 94–106 (2008).

    Article  Google Scholar 

  32. Jopp, D. & Smith, J. Resources and life-management strategies as determinants of successful aging: on the protective effect of selection, optimization, and compensation. Psychol. Aging 21, 253–265 (2006).

    Article  PubMed  Google Scholar 

  33. Carpentieri, J. D., Elliott, J., Brett, C. E. & Deary, I. J. Adapting to aging: older people talk about their use of selection, optimization, and compensation to maximize well-being in the context of physical decline. 72, 351–361 (2017).

  34. Baltes, P. B. On the incomplete architecture of human ontogeny: selection, optimization, and compensation as foundation of developmental theory. Am. Psychol. 52, 366–380 (1997).

    Article  PubMed  Google Scholar 

  35. Frost, R., Beattie, A., Bhanu, C., Walters, K. & Ben-Shlomo, Y. Management of depression and referral of older people to psychological therapies: a systematic review of qualitative studies. Br. J. Gen. Pract. 69, e171–e181 (2019).

    Article  PubMed  PubMed Central  Google Scholar 

  36. Cuijpers, P. et al. Psychotherapy for depression across different age groups: a systematic review and meta-analysis. JAMA Psychiatry 77, 694–702 (2020).

    Article  PubMed  PubMed Central  Google Scholar 

  37. Fordham, B. et al. The evidence for cognitive behavioural therapy in any condition, population or context: a meta-review of systematic reviews and panoramic meta-analysis. Psychol. Med. 51, 21–29 (2021).

    Article  PubMed  PubMed Central  Google Scholar 

  38. Hall, J., Kellett, S., Berrios, R., Bains, M. K. & Scott, S. Efficacy of cognitive behavioral therapy for generalized anxiety disorder in older adults: systematic review, meta-analysis, and meta-regression. Am. J. Geriat. Psychiatry 24, 1063–1073 (2016).

    Article  Google Scholar 

  39. Jonsson, U. et al. Psychological treatment of depression in people aged 65 years and over: a systematic review of efficacy, safety, and cost-effectiveness. PLoS ONE 11, e0160859 (2016).

    Article  PubMed  PubMed Central  Google Scholar 

  40. Kishita, N. & Laidlaw, K. Cognitive behaviour therapy for generalized anxiety disorder: is CBT equally efficacious in adults of working age and older adults? Clin. Psychol. Rev. 52, 124–136 (2017).

    Article  PubMed  Google Scholar 

  41. Werson, A. D., Meiser-Stedman, R. & Laidlaw, K. A meta-analysis of CBT efficacy for depression comparing adults and older adults. J. Affect. Disord. 319, 189–201 (2022).

    Article  PubMed  Google Scholar 

  42. Chaplin, R., Farquharson, L., Clapp, M. & Crawford, M. Comparison of access, outcomes and experiences of older adults and working age adults in psychological therapy. Int. J. Geriat. Psychiatry 30, 178–184 (2015).

    Article  Google Scholar 

  43. Saunders, R. et al. Older adults respond better to psychological therapy than working-age adults: evidence from a large sample of mental health service attendees. J. Affect. Disord. 294, 85–93 (2021).

    Article  PubMed  PubMed Central  Google Scholar 

  44. Hinrichsen, G. A. & Iselin, M.-G. in The Oxford Handbook of Clinical Geropsychology (eds Pachana, N. A. & Laidlaw, K.) Ch. 30 (Oxford Univ. Press, 2014).

  45. Bernecker, S. L., Coyne, A. E., Constantino, M. J. & Ravitz, P. For whom does interpersonal psychotherapy work? A systematic review. Clin. Psychol. Rev. 56, 82–93 (2017).

    Article  PubMed  Google Scholar 

  46. Choudhury, T. K., John, K. C., Garrett, R. K. & Stagner, B. H. Considering psychodynamic therapy for older adults. Psychodyn. Psychiatry 48, 152–162 (2020).

    Article  PubMed  Google Scholar 

  47. Gould, R. L., Coulson, M. C. & Howard, R. J. Cognitive behavioral therapy for depression in older people: a meta-analysis and meta-regression of randomized controlled trials. J. Am. Geriatr. Soc. 60, 1817–1830 (2012).

    Article  PubMed  Google Scholar 

  48. Kabat-Zinn, J. Full Catastrophe Living: Using the Wisdom of your Body and Mind to Face Stress, Pain, and Illness 15th anniv. edn (Delta Trade Paperback/Bantam Dell, 2005).

  49. Gallagher, D. E. & Thompson, L. W. Treatment of major depressive disorder in older adult outpatients with brief psychotherapies. Psychother. Theory Res. Pract. 19, 482–490 (1982).

    Article  Google Scholar 

  50. Gould, R. L., Coulson, M. C. & Howard, R. J. Efficacy of cognitive behavioral therapy for anxiety disorders in older people: a meta-analysis and meta-regression of randomized controlled trials. J. Am. Geriat. Soc. 60, 218–229 (2012).

    Article  PubMed  Google Scholar 

  51. Johnco, C. J., Dickson, S. J. & Seaton, A. A systematic review and meta-analysis of diagnostic remission, treatment response, attrition and relapse following cognitive behavior therapy (CBT), other psychological therapies and pharmacological treatments for anxiety disorders in older adults. Am. J. Geriat. Psychiatry https://doi.org/10.1016/j.jagp.2025.05.010 (2025).

  52. Orgeta, V., Brede, J. & Livingston, G. Behavioural activation for depression in older people: systematic review and meta-analysis. Br. J. Psychiatry 211, 274–279 (2017).

    Article  PubMed  Google Scholar 

  53. Shang, P. et al. Problem-solving therapy for major depressive disorders in older adults: an updated systematic review and meta-analysis of randomized controlled trials. Aging Clin. Exp. Res. 33, 1465–1475 (2021).

    Article  PubMed  Google Scholar 

  54. Hendriks, G. J. et al. Cognitive behavioural therapy and third-wave approaches for anxiety and related disorders in older people. Cochrane Database Syst. Rev. 7, Cd007674 (2024).

    PubMed  Google Scholar 

  55. Laidlaw, K. in Handbook of Cognitive Behavioral Therapy: Applications (ed. Wenzel, A.) 751–771 (American Psychological Association, 2021).

  56. Serfaty, M. A. et al. Clinical effectiveness of individual cognitive behavioral therapy for depressed older people in primary care: a randomized controlled trial. Arch. Gen. Psychiatry 66, 1332–1340 (2009).

    Article  PubMed  Google Scholar 

  57. Laidlaw, K. et al. A randomised controlled trial of cognitive behaviour therapy vs treatment as usual in the treatment of mild to moderate late life depression. Int. J. Geriat. Psychiatry 23, 843–850 (2008).

    Article  Google Scholar 

  58. Bhar, S. et al. in Comprehensive Clinical Psychology 2nd edn (ed. Asmundson, G. J. G.) 311–327 (Elsevier, 2022).

  59. Chan, P. et al. Characteristics and effectiveness of cognitive behavioral therapy for older adults living in residential care: a systematic review. Aging Ment. Health 25, 187–205 (2019).

    Article  PubMed  Google Scholar 

  60. Meeks, S., Haitsma, K. V., Schoenbachler, B. & Looney, S. W. BE-ACTIV for depression in nursing homes: primary outcomes of a randomized clinical trial. J. Gerontol. Ser. B 70, 13–23 (2015).

    Article  Google Scholar 

  61. Luo, H., Lou, V. W. Q., Chen, C. & Chi, I. The effectiveness of the positive mood and active life program on reducing depressive symptoms in long-term care facilities. Gerontologist 60, 193–204 (2020).

    PubMed  Google Scholar 

  62. Hazlett-Stevens, H., Singer, J. & Chong, A. Mindfulness-based stress reduction and mindfulness-based cognitive therapy with older adults: a qualitative review of randomized controlled outcome research. Clin. Gerontol. 42, 347–358 (2019).

    Article  PubMed  Google Scholar 

  63. Thomas, R., Chur-Hansen, A. & Turner, M. A systematic review of studies on the use of mindfulness-based cognitive therapy for the treatment of anxiety and depression in older people. Mindfulness 11, 1599–1609 (2020).

    Article  Google Scholar 

  64. Wang, F. L. et al. Effects of mindfulness-based interventions on dementia patients: a meta-analysis. West. J. Nurs. Res. 42, 1163–1173 (2020).

    Article  PubMed  Google Scholar 

  65. Han, A. Mindfulness-based interventions for older adults with dementia or mild cognitive impairment: a meta-analysis. Clin. Gerontol. 45, 763–776 (2022).

    Article  PubMed  Google Scholar 

  66. Leow, Y., Rashid, N. L. B. A., Klainin-Yobas, P., Zhang, Z. & Wu, X. V. Effectiveness of mindfulness-based interventions on mental, cognitive outcomes and neuroplastic changes in older adults with mild cognitive impairment: a systematic review and meta-analysis. J. Adv. Nurs. 79, 4489–4505 (2023).

    Article  PubMed  Google Scholar 

  67. Nagaoka, M., Hashimoto, Z., Takeuchi, H. & Sado, M. Effectiveness of mindfulness-based interventions for people with dementia and mild cognitive impairment: a meta-analysis and implications for future research. PLoS ONE 16, e0255128 (2021).

    Article  PubMed  PubMed Central  Google Scholar 

  68. Chojak, A. Effectiveness of ACT-based intervention in compliance with the model for sustainable mental health: a cluster randomized control trial in a group of older adults. J. Contextual Behav. Sci. 28, 48–59 (2023).

    Article  Google Scholar 

  69. Fashler, S. R., Weinrib, A. Z., Azam, M. A. & Katz, J. The use of acceptance and commitment therapy in oncology settings: a narrative review. Psychol. Rep. 121, 229–252 (2018).

    Article  PubMed  Google Scholar 

  70. Reskati, M. H., Mirzaian, B. & Hosseini, S. H. A Systematic review and meta-analysis of acceptance and commitment therapy on mental health and quality of life of women with breast cancer. J. Mazandaran Univ. Med. Sci. 28, 192–207 (2018).

    Google Scholar 

  71. Mathew, A., Doorenbos, A. Z., Jang, M. K. & Hershberger, P. E. Acceptance and commitment therapy in adult cancer survivors: a systematic review and conceptual model. J. Cancer Surviv. 15, 427–451 (2021).

    Article  PubMed  Google Scholar 

  72. González-Fernández, S. & Fernández-Rodríguez, C. Acceptance and commitment therapy in cancer: review of applications and findings. Behav. Med. 45, 255–269 (2019).

    Article  PubMed  Google Scholar 

  73. Li, H. et al. Effects of acceptance and commitment therapy on health-related outcomes for patients with advanced cancer: a systematic review. Int. J. Nurs. Stud. 115, 103876 (2021).

    Article  PubMed  Google Scholar 

  74. Graham, C. D., Gouick, J., Krahé, C. & Gillanders, D. A systematic review of the use of acceptance and commitment therapy (ACT) in chronic disease and long-term conditions. Clin. Psychol. Rev. 46, 46–58 (2016).

    Article  PubMed  Google Scholar 

  75. Rashidi, A. et al. The role of acceptance and commitment therapy in cardiovascular and diabetes healthcare: a scoping review. Int. J. Environ. Res. Public Health 18, 8126 (2021).

    Article  PubMed  PubMed Central  Google Scholar 

  76. Sakamoto, R. et al. Efficacy of acceptance and commitment therapy for people with type 2 diabetes: systematic review and meta-analysis. J. Diabetes Invest. 13, 262–270 (2022).

    Article  Google Scholar 

  77. Hughes, L. S., Clark, J., Colclough, J. A., Dale, E. & McMillan, D. Acceptance and commitment therapy (ACT) for chronic pain: a systematic review and meta-analyses. Clin. J. Pain 33, 552–568 (2017).

    Article  PubMed  Google Scholar 

  78. Han, A. Mindfulness- and acceptance-based interventions for stroke survivors: a systematic review and meta-analysis. Rehab. Couns. Bull. 66, 123–135 (2023).

    Article  Google Scholar 

  79. Witlox, M. et al. Blended acceptance and commitment therapy versus face-to-face cognitive behavioral therapy for older adults with anxiety symptoms in primary care: pragmatic single-blind cluster randomized trial. J. Med. Internet Res. 23, e24366 (2021).

    Article  PubMed  PubMed Central  Google Scholar 

  80. Ji, M. et al. Comparative effectiveness and acceptability of psychotherapies for late-life depression: a systematic review and network meta-analysis. J. Affect. Disord. 323, 409–416 (2023).

    Article  PubMed  Google Scholar 

  81. Davison, T. E. et al. Psychological therapies for depression in older adults residing in long-term care settings. Cochrane Database Syst. Rev. https://doi.org/10.1002/14651858.CD013059.pub2 (2024).

  82. Bhar, S. S. in Oxford Handbook of Geropsychology (eds Pachana, N. A. & Laidlaw, K.) 675–690 (Oxford Univ. Press, 2014).

  83. Webster, J., Bohlmeijer, E. T. & Westerhof, G. J. Mapping the future of reminiscence: a conceptual guide for research and practice. Res. Aging 32, 527–564 (2010).

    Article  Google Scholar 

  84. Fu, S. R., Lee, M. F. & Ou, S. J. Effects of reminiscing about nostalgic smells on the physiological and psychological responses of older people in long-term care facilities. Ageing Soc. 40, 501–511 (2020).

    Article  Google Scholar 

  85. Haight, B. K. & Haight, B. S. The Handbook of Structured Life Review (Health Professions Press, 2007).

  86. James, K. L. & Bhar, S. S. Brief reminiscence intervention improves affect and pessimism in non-clinical individuals: a pilot study. Clin. Psychol. https://doi.org/10.1111/cp.12068 (2015).

  87. Xu, L. et al. Effects of reminiscence therapy on psychological outcome among older adults without obvious cognitive impairment: a systematic review and meta-analysis. Front. Psychiatry 14, https://doi.org/10.3389/fpsyt.2023.1139700 (2023).

  88. Huang, H. C. et al. Reminiscence therapy improves cognitive functions and reduces depressive symptoms in elderly people with dementia: a meta-analysis of randomized controlled trials. J. Am. Med. Dir. Assoc. 16, 1087–1094 (2015).

    Article  PubMed  Google Scholar 

  89. Gil, I. et al. Efficacy of reminiscence in cognition, depressive symptoms and quality of life in institutionalized elderly: a systematic review. Rev. Escola Enfermagem 53, https://doi.org/10.1590/S1980-220X2018007403458 (2019).

  90. Kim, K. & Lee, J. Effects of reminiscence therapy on depressive symptoms in older adults with dementia: a systematic review and meta-analysis. J. Korean Acad. Nurs. 49, 225–240 (2019).

    Article  PubMed  Google Scholar 

  91. Saragih, I. D., Tonapa, S. I., Yao, C. T., Saragih, I. S. & Lee, B. O. Effects of reminiscence therapy in people with dementia: a systematic review and meta-analysis. J. Psychiat. Ment. Health Nurs. 29, 883–903 (2022).

    Article  Google Scholar 

  92. Woods, B., O’Philbin, L., Farrell, E. M., Spector, A. E. & Orrell, M. Reminiscence therapy for dementia. Cochrane Database Syst. Rev. 3, CD001120 (2018).

    PubMed  Google Scholar 

  93. Wells, Y. et al. What Works to Promote Emotional Wellbeing in Older People (BeyondBlue, 2014).

  94. Brownie, S. & Horstmanshof, L. The management of loneliness in aged care residents: an important therapeutic target for gerontological nursing. Geriatric Nurs. 32, 318–325 (2011).

    Article  Google Scholar 

  95. Quan, N. G., Lohman, M. C., Resciniti, N. V. & Friedman, D. B. A systematic review of interventions for loneliness among older adults living in long-term care facilities. Aging Mental Health https://doi.org/10.1080/13607863.2019.1673311 (2019).

  96. Mohlman, J. A community based survey of older adults’ preferences for treatment of anxiety. Psychol. Aging 27, 1182–1190 (2012).

    Article  PubMed  Google Scholar 

  97. Gum, A. M., Iser, L. & Petkus, A. Behavioral health service utilization and preferences of older adults receiving home-based aging services. Am. J. Geriat. Psychiatry 18, 491–501 (2010).

    Article  Google Scholar 

  98. Morgado, B. et al. Psychotherapeutic interventions for depressive symptoms in community-dwelling older adults: a systematic review with meta-analysis. Healthcare 12, 2551 (2024).

    Article  PubMed  PubMed Central  Google Scholar 

  99. Laidlaw, K., Thompson, L. W. & Gallagher-Thompson, D. Comprehensive conceptualization of cognitve behaviour therapy for late life depression. Behav. Cogn. Psychother. 32, 389–399 (2004).

    Article  Google Scholar 

  100. Laidlaw, K. CBT for Older People: an Introduction (Sage, 2015).

  101. Bilbrey, A. C., Laidlaw, K., Cassidy-Eagle, E., Thompson, L. W. & Gallagher-Thompson, D. Cognitive behavioral therapy for late-life depression: evidence, issues, and recommendations. Cogn. Behav. Pract. 29, 128–145 (2022).

    Article  Google Scholar 

  102. Laidlaw, K., Kishita, N. & Chellingsworth, M. A Clinician’s Guide To CBT With Older People. https://www.uea.ac.uk/about/norwich-medical-school/resources/improving-access-to-psychological-therapies-and-cognitive-behavioural-therapies-resources/older-people-resources (Univ. East Anglia, 2016).

  103. Kadri, A., Leddy, A., Gracey, F. & Laidlaw, K. Wisdom enhancement and life skills to augment CBT outcomes for depression in later life: a series of N-of-1 trials. Behav. Cogn. Psychother. 50, 508–527 (2022).

    Article  PubMed  Google Scholar 

  104. Salkovskis, P. M., Sighvatsson, M. B. & Sigurdsson, J. F. How effective psychological treatments work: mechanisms of change in cognitive behavioural therapy and beyond. Behav. Cogn. Psychother. 51, 595–615 (2023).

    Article  PubMed  Google Scholar 

  105. McAdams, D. P., Trzesniewski, K., Lilgendahl, J., Benet-Martinez, V. & Robins, R. W. Self and identity in personality psychology. Personality Sci. 2, e6035 (2021).

    Article  Google Scholar 

  106. Levy, B. Stereotype embodiment: a psychosocial approach to aging. Curr. Dir. Psychol. Sci. 18, 332–336 (2009).

    Article  PubMed  PubMed Central  Google Scholar 

  107. Reynolds, C. F. 3rd, Jeste, D. V., Sachdev, P. S. & Blazer, D. G. Mental health care for older adults: recent advances and new directions in clinical practice and research. World Psychiatry 21, 336–363 (2022).

    Article  PubMed  PubMed Central  Google Scholar 

  108. Chang, E. S. et al. Global reach of ageism on older persons’ health: a systematic review. PLoS ONE 15, e0220857 (2020).

    Article  PubMed  PubMed Central  Google Scholar 

  109. Chonody, J. M., Webb, S. N., Ranzijn, R. & Bryan, J. Working with older adults: predictors of attitudes towards ageing in psychology and social work students, faculty, and practitioners. Aust. Psychol. 49, 374–383 (2014).

    Article  Google Scholar 

  110. Barnett, M. D. & Adams, C. M. Ageism and aging anxiety among young adults: relationships with contact, knowledge, fear of death, and optimism. Educ. Gerontol. 44, 693–700 (2018).

    Article  Google Scholar 

  111. Caskie, G. I. L., Patterson, S. L. & Voelkner, A. R. Health bias in clinical work with older adult clients: the relation with ageism and aging anxiety. Clin. Gerontol. 45, 351–365 (2022).

    Article  PubMed  Google Scholar 

  112. Caskie, G. I. L., Sutton, M. C. & Voelkner, A. R. Clinical and counseling psychology doctoral trainees’ attitudes toward and interest in working with older adult clients. Gerontol. Geriat. Educ. 45, 141–155 (2024).

    Article  Google Scholar 

  113. Charlesworth, G. Embedding the silver thread in all-age psychological services: training and supervising younger therapists to deliver CBT for anxiety or depression to older people with multi-morbidity. Cogn. Behav. Therapist 15, e49 (2022).

    Article  Google Scholar 

  114. Law, J., Laidlaw, K. & Peck, D. Is depression viewed as an inevitable consequence of age? The “understandability phenomenon” in older people. Clin. Gerontol. 33, 194–209 (2010).

    Article  Google Scholar 

  115. Garrison-Diehn, C., Rummel, C., Au, Y. H. & Scherer, K. Attitudes toward older adults and aging: a foundational geropsychology knowledge competency. Clin. Psychol. Sci. Pract. 29, 4–15 (2022).

    Article  Google Scholar 

  116. Apriceno, M. & Levy, S. R. Systematic review and meta-analyses of effective programs for reducing ageism toward older adults. J. Appl. Gerontol. 42, 1356–1375 (2023).

    Article  PubMed  Google Scholar 

  117. Burnes, D. et al. Interventions to reduce ageism against older adults: a systematic review and meta-analysis. Am. J. Public. Health 109, e1–e9 (2019).

    Article  PubMed  PubMed Central  Google Scholar 

  118. Martínez-Arnau, F. M., López-Hernández, L., Castellano-Rioja, E., Botella-Navas, M. & Pérez-Ros, P. Interventions to improve attitudes toward older people in undergraduate health and social sciences students. A systematic review and meta-analysis. Nurse Educ. Today 110, 105269 (2022).

    Article  PubMed  Google Scholar 

  119. Rababa, M., Alhawatmeh, H., Al Ali, N. & Kassab, M. Testing the effectiveness of cognitive behavioral therapy in relieving nurses’ ageism toward older adults: a randomized controlled trial. Cogn. Ther. Res. 45, 355–366 (2021).

    Article  Google Scholar 

  120. Harvey, A. G. et al. Improving outcome of psychosocial treatments by enhancing memory and learning. Persp. Psychol. Sci. 9, 161–179 (2014).

    Article  Google Scholar 

  121. De Vito, A. N., Ahmed, M. & Mohlman, J. Cognitive enhancement strategies to augment cognitive-behavioral therapy for anxiety and related disorders: rationale and recommendations for use with cognitively healthy older adults. Cogn. Behav. Pract. 29, 175–184 (2022).

    Article  Google Scholar 

  122. Mohlman, J. More power to the executive? A preliminary test of CBT plus executive skills training for treatment of late-life GAD. Cogn. Behav. Pract. 15, 306–316 (2008).

    Article  Google Scholar 

  123. Mohlman, J., DeVito, A., Lauderdale, S. & Dobkin, R. Initial outcomes of a combined cognitive–behavioral therapy and attention process training intervention for older adults with Parkinson’s disease. Pract. Innov. 2, 234–242 (2017).

    Article  Google Scholar 

  124. Harvey, A. G. et al. Improving outcome for mental disorders by enhancing memory for treatment. Behav. Res. Ther. 81, 35–46 (2016).

    Article  PubMed  PubMed Central  Google Scholar 

  125. Dong, L. et al. Can integrating the memory support intervention into cognitive therapy improve depression outcome? A randomized controlled trial. Behav. Res. Ther. 157, 104167 (2022).

    Article  PubMed  Google Scholar 

  126. Sarfan, L. D., Zieve, G., Gumport, N. B., Xiong, M. & Harvey, A. G. Optimizing outcomes, mechanisms, and recall of cognitive therapy for depression: dose of constructive memory support strategies. Behav. Res. Ther. 166, 104325 (2023).

    Article  PubMed  PubMed Central  Google Scholar 

  127. Kiosses, D. N. Problem adaptation therapy (PATH): origins, current status, and future directions. Am. J. Geriat. Psychiatry 30, 922–924 (2022).

    Article  Google Scholar 

  128. Howard, R. et al. Adapted problem adaptation therapy for depression in mild to moderate Alzheimer’s disease dementia: a randomized controlled trial. Alzheimers Dement. 20, 2990–2999 (2024).

    Article  PubMed  PubMed Central  Google Scholar 

  129. Schulz, R., Beach, S. R., Czaja, S. J., Martire, L. M. & Monin, J. K. Family caregiving for older adults. Annu. Rev. Psychol. 71, 635–659 (2020).

    Article  PubMed  PubMed Central  Google Scholar 

  130. Hopkinson, M. D., Reavell, J., Lane, D. A. & Mallikarjun, P. Cognitive behavioral therapy for depression, anxiety, and stress in caregivers of dementia patients: a systematic review and meta-analysis. Gerontologist 59, e343–e362 (2019).

    Article  PubMed  Google Scholar 

  131. Kaddour, L., Kishita, N. & Schaller, A. A meta-analysis of low-intensity cognitive behavioral therapy-based interventions for dementia caregivers. Int. Psychogeriat. 31, 961–976 (2019).

    Article  Google Scholar 

  132. Kwon, O. Y., Ahn, H. S., Kim, H. J. & Park, K. W. Effectiveness of cognitive behavioral therapy for caregivers of people with dementia: a systematic review and meta-analysis. J. Clin. Neurol. 13, 394–404 (2017).

    Article  PubMed  PubMed Central  Google Scholar 

  133. Sun, Y. et al. Comparative efficacy of 11 non-pharmacological interventions on depression, anxiety, quality of life, and caregiver burden for informal caregivers of people with dementia: a systematic review and network meta-analysis. Int. J. Nurs. Stud. 129, 104204 (2022).

    Article  PubMed  Google Scholar 

  134. Sun, Y., Ji, M., Leng, M. & Wang, Z. Which cognitive behavioral therapy delivery formats work for depressive symptoms in dementia caregivers? A systematic review and network meta-analysis of randomized controlled trials. J. Affect. Disord. 308, 181–187 (2022).

    Article  PubMed  Google Scholar 

  135. Kor, P. P. K., Liu, J. Y. W. & Chien, W. T. Effects of a modified mindfulness-based cognitive therapy for family caregivers of people with dementia: a pilot randomized controlled trial. Int. J. Nurs. Stud. 98, 107–117 (2019).

    Article  PubMed  Google Scholar 

  136. Liu, Z., Sun, Y. Y. & Zhong, B. L. Mindfulness-based stress reduction for family carers of people with dementia. Cochrane Database Syst. Rev. 8, Cd012791 (2018).

    PubMed  Google Scholar 

  137. Cheng, S.-T., Li, K.-K., Or, P. P. L. & Losada, A. Do caregiver interventions improve outcomes in relatives with dementia and mild cognitive impairment? A comprehensive systematic review and meta-analysis. Psychol. Aging 37, 929–953 (2022).

    Article  PubMed  Google Scholar 

  138. Cheng, S. T., Chan, W. C. & Lam, L. C. W. Are care-recipient outcomes attributable to improved caregiver well-being? A cluster-randomized controlled trial of benefit-finding intervention. Am. J. Geriat. Psychiatry 30, 903–913 (2022).

    Article  Google Scholar 

  139. Klein, D., Pendergrass, A., Becker, C., Hautzinger, M. & Pfeiffer, K. Dementia caregiver interventions: a systematic review of care recipient outcome measures. Int. J. Emerg. Ment. Health 17, 451–426 (2015).

    Google Scholar 

  140. Tomko, J. K. & Munley, P. H. Predicting counseling psychologists attitudes and clinical judgments with respect to older adults. Aging Ment. Health 17, 233–241 (2013).

    Article  PubMed  Google Scholar 

  141. Sue, D. W., Arredondo, P. & McDavis, R. J. Multicultural counseling competencies and standards: a call to the profession. J. Multicult. Couns. Dev. 20, 64–88 (1992).

    Article  Google Scholar 

  142. Charlesworth, T. E. S., Navon, M., Rabinovich, Y., Lofaro, N. & Kurdi, B. The Project Implicit: International dataset: measuring implicit and explicit social group attitudes and stereotypes across 34 countries (2009–2019). Behav. Res. Meth. 55, 1413–1440 (2023).

    Article  Google Scholar 

  143. Anik, E., West, R. M., Cardno, A. G. & Mir, G. Culturally adapted psychotherapies for depressed adults: a systematic review and meta-analysis. J. Affect. Disord. 278, 296–310 (2021).

    Article  PubMed  Google Scholar 

  144. Silveus, S. A., Schmit, M. K., Oliveira, J. T. & Hughes, L. E. Meta-analysis of culturally adapted cognitive behavioral therapy for anxiety and depression. J. Couns. Dev. 101, 129–142 (2023).

    Article  Google Scholar 

  145. Lau, A. W. & Kinoshita, L. M. in Culturally Responsive Cognitive-Behavioral Therapy: Assessment, Practice, and Supervision (eds Hays, P. A. & Iwamasa, G. Y.) 179–197 (American Psychological Association, 2006).

  146. Hilberdink, C. E. et al. Bereavement issues and prolonged grief disorder: a global perspective. Camb. Prisms Glob. Ment. Health 10, e32 (2023).

    Google Scholar 

  147. Knight, B. G. & Sayegh, P. Cultural values and caregiving: the updated sociocultural stress and coping model. 65b, 5–13 (2010).

  148. Gallagher-Thompson, D., Gray, H. L., Dupart, T., Jimenez, D. & Thompson, L. W. Effectiveness of cognitive/behavioral small group intervention for reduction of depression and stress in non-hispanic white and Hispanic/Latino women dementia family caregivers: outcomes and mediators of change. J. Ration. Emot. Cogn. Behav. Ther. 26, 286–303 (2008).

    Article  PubMed  PubMed Central  Google Scholar 

  149. Au, A. et al. The Coping With Caregiving group program for Chinese caregivers of patients with Alzheimer’s disease in Hong Kong. Patient Educ. Couns. 78, 256–260 (2010).

    Article  PubMed  Google Scholar 

  150. Livingston, G. et al. Clinical effectiveness of a manual based coping strategy programme (START, STrAtegies for RelaTives) in promoting the mental health of carers of family members with dementia: pragmatic randomised controlled trial. BMJ 347, f6276 (2013).

    Article  PubMed  PubMed Central  Google Scholar 

  151. Livingston, G. et al. Clinical effectiveness of the START (STrAtegies for RelaTives) psychological intervention for family carers and the effects on the cost of care for people with dementia: 6-year follow-up of a randomised controlled trial. Br. J. Psychiatry 216, 35–42 (2020).

    Article  PubMed  Google Scholar 

  152. Loi, S. M. et al. START-online: acceptability and feasibility of an online intervention for carers of people living with dementia. Pilot Feasibility Stud. 8, 41 (2022).

    Article  PubMed  PubMed Central  Google Scholar 

  153. Webster, L. et al. Tailoring STrAtegies for relatives for Black and South Asian dementia family carers in the United Kingdom: a mixed methods study. Int. J. Geriat. Psychiatry 38, e5868 (2023).

    Article  Google Scholar 

  154. Reangsing, C., Rittiwong, T. & Schneider, J. K. Effects of mindfulness meditation interventions on depression in older adults: a meta-analysis. Aging Ment. Health 25, 1181–1190 (2021).

    Article  PubMed  Google Scholar 

  155. Stead, A., Flahive, M., Fitzgerald, C. & Frost, M. Generational considerations for counseling older adults. Persp. ASHA Spec. Interest Groups 2, 42–52 (2017).

    Article  Google Scholar 

  156. Knight, B. G., Karel, M. J., Hinrichsen, G. A., Qualls, S. H. & Duffy, M. Pikes Peak model for training in professional geropsychology. Am. Psychol. 64, 205–214 (2009).

    Article  PubMed  Google Scholar 

  157. Levy, S. R. Toward reducing ageism: PEACE (Positive Education about Aging and Contact Experiences) model. Gerontologist 58, 226–232 (2018).

    PubMed  Google Scholar 

  158. Webster, M., Norwood, K., Waterworth, J. & Leavey, G. Effectiveness of intergenerational exchange programs between adolescents and older adults: a systematic review. J. Intergen. Relat. 22, 603–644 (2024).

    Google Scholar 

  159. Petersen, J. A meta-analytic review of the effects of intergenerational programs for youth and older adults. Educ. Gerontol. 49, 175–189 (2023).

    Article  Google Scholar 

  160. NHS talking therapies positive practice guide: older people. British Association for Counselling and Psychotherapy (BABCP) https://babcp.com/guidelines-and-policies/older-adults-positive-practice-guide/ (2024).

  161. Assfaw, A. D. et al. Assessing culturally tailored dementia interventions to support informal caregivers of people living with dementia (PLWD): a scoping review. J. Racial Ethnic Health Dispar. 12, 1526–1543 (2025).

    Article  Google Scholar 

  162. Gaviola, M. A., Omura, M., Inder, K. J. & Johnson, A. Caring for people with dementia from culturally and linguistically diverse backgrounds in nursing homes: a scoping review. Int. J. Nurs. Stud. 151, 104674 (2024).

    Article  PubMed  Google Scholar 

  163. Holvast, F., Massoudi, B., Oude Voshaar, R. C. & Verhaak, P. F. M. Non-pharmacological treatment for depressed older patients in primary care: a systematic review and meta-analysis. PLoS ONE 12, e0184666 (2017).

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Acknowledgements

We thank those of our clients who have allowed us to use their clinical examples to illustrate our work. Their generosity and willingness to share information is truly appreciated.

Author information

Authors and Affiliations

Authors

Contributions

The authors contributed equally to all aspects of the article.

Corresponding author

Correspondence to Ken Laidlaw.

Ethics declarations

Competing interests

The authors declare no competing interests.

Peer review

Peer review information

Nature Reviews Psychology thanks Lydia Morris and the other, anonymous, reviewer(s) for their contribution to the peer review of this work.

Additional information

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Laidlaw, K., Charlesworth, G. & Bhar, S. Mental health and treatment challenges in older adults. Nat Rev Psychol (2025). https://doi.org/10.1038/s44159-025-00500-7

Download citation

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1038/s44159-025-00500-7

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing