The deuteration of organic compounds typically requires harsh conditions. Now, a scalable photocatalytic method is developed for the deuteration of N-heteroarenes in D2O at room temperature under visible light irradiation and an inert atmosphere over an atomically dispersed palladium photocatalyst.
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References
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This is a summary of: Xu, J. et al. Scalable light-driven deuteration of N-heteroarenes over atomically dispersed palladium. Nat. Synth. https://doi.org/10.1038/s44160-025-00975-5 (2026).
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Scalable photocatalytic deuteration of N-heteroarenes. Nat. Synth (2026). https://doi.org/10.1038/s44160-025-00978-2
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DOI: https://doi.org/10.1038/s44160-025-00978-2
