Extended Data Fig. 2: Expression of TRPM2 is increased during atherogenesis.

(a, b) Representative WB analysis of TRPM2 expression in aorta from wild-type mice (WT) with or without the treatment of high-fat diet (HFD) for 4 months (n = 6/group). (c, d) Representative WB analysis of TRPM2 expression in macrophages isolated from WT mice with or without the treatment of oxLDL (50 µg/ml) for 24 h (n = 6/group). (***: p < 0.001; unpaired t test, two-tailed; mean ± SEM)