Extended Data Fig. 2: Vascular lesion analysis.

(A) Representative image of Oil Red O-stained aortic root in control and Smad3ΔSMC mice, (B) quantified total Oil Red O positive area, and (C) quantified fraction of plaque Oil Red O staining (total Oil Red-O positive area over plaque area). (D) Representative image of trichrome stained aortic root in control and Smad3ΔSMC, with (E) quantified total acellular area, and (F) quantified normalized plaque acellular fraction (total acellular area over plaque area). Scale bar: 50um.