Extended Data Fig. 2: Cardiomyocyte-conditioned medium induces FSP-1 and α-SMA expression in ECs.

Mouse cardiac-conditioned medium (CCM) were harvested from primary mouse cardiomyocytes cultured under hypoxia (1% O2). Mouse cardiac microvascular ECs were treated with CCM under normoxia or hypoxia for 2 days. Cell lysates were immunoblotted. These experiments were repeated independently twice with similar results.