Extended Data Fig. 3: Expression of mesenchymal genes in MI-associated ECs.
MI was induced in wild-type mice. Three weeks after MI induction, ECs were isolated from normal LV and MI tissues. RNA was extracted and subjected to RT-PCR analysis (mean ± SEM, n = 5-7 mice, specific n indicated in the graphs). Statistical analysis by unpaired two-tailed Students’ t test. Expression of (a) S100A4 (FSP-1) and Acta2 (α-SMA), and (b) Snai1 (Snail), Snai2 (Slug), and Twist1 was normalized with GAPDH expression levels.
