Extended Data Fig. 8: PDGFR-β knockout reduces Snail expression in MI-associated ECs.

MI was induced in WT and PDGFR-β-ΔEC mice. (a,b) 14 and (c,d) 28 days after MI induction, MI tissue sections were collected and subjected to single-nuclei RNA sequencing analysis (total = 4 mice). Uniform manifold approximation and projection (UMAP) analysis of transcriptome gene signature in ECs. (a,c) UMAP analysis of ECs. (b,d) Expression of Snail, Slug, and Ki67 in ECs.