Extended Data Fig. 9: PDGFR-β knockout in ECs alters expression of metabolism-associated genes in myocytes.

MI was induced in WT and PDGFR-β-ΔEC mice. 14 and 28 days after MI induction, MI tissue sections were collected and subjected to single-nuclei RNA sequencing analysis (total = 4 mice). Expression of metabolism-associated genes were analyzed. a, Heatmap of mapped genes. b, Global changes in gene expression at days 14 and 28 after MI induction.