Fig. 3: Regression analysis.
From: Genetic and environmental determinants of diastolic heart function
a, Multiple linear regression analysis of left ventricular PDSRll, PDSRrr and indexed LAVmaxi with age, sex, BSA, SBP, pulse rate and diabetes as predictors. All associations were significant after false discovery rate (FDR) correction. Data are presented as beta coefficient point estimates (95% CI). b, Circular plot visualization of the associations between the imaging (red, PDSRll, PDSRrr, global systolic radial strain (Err), global systolic longitudinal strain (Ell), ascending aortic (AAo) distensibility, descending aortic (DAo) distensibility, indexed left ventricular stroke volume (LVSVi), left ventricular cardiac index (LVCI), LAVmaxi, indexed right ventricular stroke volume (RVSVi) and right atrial ejection fraction (RAEF) and the non-imaging phenotypes (green for environmental; blue for biochemical). The strength of the connection between each pair is presented as a ribbon with a size proportional to the regression coefficient. All associations with a regression coefficient <0.3 are shown in faint colors (apart from the associations between PDSRll, PDSRrr and LAVmaxi and all other phenotypes). The coefficients for the associations of the circular plot are shown in Extended Data Fig. 4b. Standardized beta coefficients are shown with units in s.d. for each variable.
