Extended Data Fig. 4: UMAPs of Th1 and Tmem, and signature genes and molecule expressions. | Nature Cardiovascular Research

Extended Data Fig. 4: UMAPs of Th1 and Tmem, and signature genes and molecule expressions.

From: Single cell transcriptomics and TCR reconstruction reveal CD4 T cell response to MHC-II-restricted APOB epitope in human cardiovascular disease

Extended Data Fig. 4

a, UMAP with Louvain clustering of all 16,644 cells. b, c, UMAP of Th1 (b) and Tmem (c) highlighted in red. Other cells light grey. d, Expression levels of Th1 signature genes on 4 cell types. TBX21 and IFNG expressions are shown. Dot plot: fraction of cells in cluster expressing each gene shown by size of circle and level of expression shown from white (=0) to dark blue (=max, log2 scale). e We checked FoxP3 expression in CD3+CD4+CD127-CD25+ cells and the percentage was 91.3±4.06% (Mean±SD), The representative image of plots and the histogram of FoxP3 expression was shown.

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