Extended Data Fig. 9: Pipeline for staging the specimens from the study of Nodal loss of function.

a, Steps taken for the image acquisition and segmentation of the Nodal mutant and control specimen series. b, Correlation between the h/w staging parameter independently measured in the SMM and MT labs. c, Mapping of the d1/d2 values measured in SMM’s control specimen collection. d, Procedure for the morphological mapping of the SMM’s control specimen collection to the atlas MSG collection. e, Correlation between the experimentally determined d1/d2 parameter and the predicted d1/d2 obtained from the morphological mapping of the SMM’s control specimen collection to the atlas MSG collection.