Extended Data Fig. 4: Heat maps of genes involved in ATP/lipids metabolism and mitochondria in postnatal day 7 GR-cKO versus controls hearts. | Nature Cardiovascular Research

Extended Data Fig. 4: Heat maps of genes involved in ATP/lipids metabolism and mitochondria in postnatal day 7 GR-cKO versus controls hearts.

From: Glucocorticoid receptor antagonization propels endogenous cardiomyocyte proliferation and cardiac regeneration

Extended Data Fig. 4

(a-b) Heat maps of statistically significant differentially expressed genes (pvalue < 0.05) by RNA-Seq transcriptome analysis of P7 GR-cKO versus control hearts (n = 6 mice) according to the following Biological Process gene ontology terms: (a) ATP metabolic process (GO:0046034) and (b) lipid metabolic process (GO:0006629); (c-d) Heat maps of statistically significant downregulated (c) or upregulated (d) genes (pvalue < 0.05) by RNA-Seq transcriptome analysis of P7 GR-cKO versus control hearts (n = 6 mice) according to Cellular Components gene ontology term ‘mitochondrion’ (GO:0005739).

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