Fig. 2: Factors affecting discordance.
Box and whisker plots demonstrating the difference between concordant (white boxes) and discordant (shaded boxes) cases in each FFR subgroup on the basis of aMVR (a), vessel diameter (b) and myocardial jeopardy (c). The direction of these differences is associated with discordance between absolute and fractional coronary blood flow changes. Concordance was 100% in the FFR <0.70 group, hence the absence of a plot for this subgroup. The box defines the IQR; the line and ‘x’ indicate the median and mean; and the bars represent variability outside the upper and lower quartiles, excluding outliers. Asterisks indicate statistical significance at the P ≤ 0.05 level (P values for a are all <0.001; P values for b are 0.03 and 0.02; and P values for c are 0.018, 0.019 and 0.021—calculated in Rstudio (two-sided Mann–Whitney U-test) with no adjustment for multiple comparisons). The numbers in gray indicate n for each group in each comparison (no replicates).
