Extended Data Fig. 7: Colocalization of immune and fibroblast subsets across time. | Nature Cardiovascular Research

Extended Data Fig. 7: Colocalization of immune and fibroblast subsets across time.

From: Single-cell and spatial transcriptomics of the infarcted heart define the dynamic onset of the border zone in response to mechanical destabilization

Extended Data Fig. 7

(a) Spatial plots showing subclustering results (shown in 3c) across 72 hrs post-MI and 168 hrs post-MI replicates. (b) Colocalized immune subsets in 72 hrs post-MI replicate. (c) Spatially correlated and clustered gene-set scores. (d) Spatially correlated and clustered genes based on spearman rank correlation analysis for all regions (left) and infarct zone (right) of 72 hrs post-MI sample. (e) All gene-set scores projected to clusters. (f) Volcano plot comparing gene-set scores in BZ1 and BZ2 (Wilcoxon Ranked Sum Test, two-sided).

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