Extended Data Fig. 4: Plaque transcriptomics. | Nature Cardiovascular Research

Extended Data Fig. 4: Plaque transcriptomics.

From: Transcriptomic-based clustering of human atherosclerotic plaques identifies subgroups with different underlying biology and clinical presentation

Extended Data Fig. 4

a) Bioanalyzer profiles of total RNA isolated from 10 random samples of advanced atherosclerotic lesions. b) Distribution of sequencing reads between samples using four different library preparation strategies. (n = 12 per library preparation method, in the case of SMARTer n = 6) c) Percentage of sequenced reads mapped to annotated genes using four different library preparation strategies. (n = 12 per library preparation method, in the case of SMARTer n = 6) Boxplot’s top, middle, and bottom lines in c) and d) represent values at 25th, 50th, and 75th percentile. Whiskers extend up to 1.5 times the interquartile range from the top (bottom) of the box to the furthest data point within that distance. d) Number of annotated genes identified per sample with at least one mapped read. Samples with less than 9000 genes were excluded from the analysis e) Number of non-ribosomal protein-coding genes with annotated HGNC name per sample used in the analysis.

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