Extended Data Fig. 3: Pf4-Cre+Gucy1b1LoxP/LoxPLdlr−/− compared to Pf4-Cre+Gucy1b1+/LoxPLdlr−/− mice after Western diet (see Fig. 1e). | Nature Cardiovascular Research

Extended Data Fig. 3: Pf4-Cre+Gucy1b1LoxP/LoxPLdlr−/− compared to Pf4-Cre+Gucy1b1+/LoxPLdlr−/− mice after Western diet (see Fig. 1e).

From: Loss of soluble guanylyl cyclase in platelets contributes to atherosclerotic plaque formation and vascular inflammation

Extended Data Fig. 3

a. Serum cholesterol levels (n = 11). b. Platelet count (n = 11). c. Body weight (n = 11) at baseline (left) and after ten weeks (right). d. Blood leukocyte numbers and subsets (n = 11 for controls, n = 10 for Pf4-Cre+Gucy1b1LoxP/LoxPLdlr−/−). Each symbol represents one independent animal. Two-sided unpaired t-test (except C 10 weeks: two-sided Mann-Whitney U-test). One outlier was removed in the analysis of D according to the ROUT method. Data are mean and s.e.m.

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