Extended Data Fig. 7: Specific GO terms for differentially expressed genes within selected groups.

Differentially expressed genes were defined as FDR < 0.05 and |log2(FC) | > 1 and submitted to the GO over-representation test. Significant GO terms (FDR < 0.05) were selected for each group, and log2(FDR) values were used for score calculation. Each cluster color (hierarchical clustering to the right of the heatmap) is numbered (number in a circle). Pathways corresponding to each cluster number are listed. Full clustering information (numbers in circles based on hierarchical clustering) is available in Source Data Extended Data Fig. 7 (column “cluster”).