Extended Data Fig. 3: Mediated Effects of Candidate Varicose Vein Risk Loci. | Nature Cardiovascular Research

Extended Data Fig. 3: Mediated Effects of Candidate Varicose Vein Risk Loci.

From: Genetics of varicose veins reveals polygenic architecture and genetic overlap with arterial and venous disease

Extended Data Fig. 3

Genomic Structural Equation Modeling was used to estimate the direct and indirect effects of rs62033413 (located near FTO) and rs6025 (Factor V Leiden) on Varicose Veins after accounting for the effects of each variant on BMI and venous thromboembolism (VTE), respectively. Error bars represent 95% Confidence Intervals (95% CI).

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