Extended Data Fig. 3: Epidemiological causal inference analysis for CHIP on incident peripheral artery disease in the UK Biobank.
From: TP53-mediated clonal hematopoiesis confers increased risk for incident atherosclerotic disease
a) Propensity scores by CHIP and Large CHIP status in the UKB (n = 37,657). b) Propensity score adjustment and stabilized inverse probability treatment weighting (IPTW) for the CHIP and Large CHIP association with incident PAD in the UKB. Error bars are centered at the HR and show the 95% CI for estimates. CHIP = clonal hematopoiesis of indeterminate potential; VAF = variant allele fraction; PAD = peripheral artery disease.
