Fig. 5: Enriched interaction pathways between CD4+ Teff cells and TREMhi macrophages.

Heat maps displaying outgoing (ligand) (a) and incoming (receptor) (b) signalling patterns of pathways describing potential ligand–receptor interactions. Scale above the heat map indicates the relative signalling strength of a cell cluster based on all signalling pathways displayed in the heat map. Grey bars to the right of the heat map show the total signalling strength of a pathway in all cell clusters. The relative signalling strength is indicated by ranging colour from white (low) to green (high). All cells included in these graphs originate from the plaque.