Extended Data Table 2 Univariable CMAs for the effect of empagliflozin on changes in measures of LV structure and function and of physical performance (n = 80)

From: Empagliflozin effects on iron metabolism as a possible mechanism for improved clinical outcomes in non-diabetic patients with systolic heart failure

  1. Heat map showing proportions mediated in each outcome–mediator combination. The proportions mediated reflect how much of the overall treatment effect on each of the outcome variables is affected by a potential mediator. For each outcome variable and mediator, adjustments for the respective baseline values and for predefined baseline confounders were made.