Fig. 3: SFK transcript detection in bulk RNA-seq data from primary human and mouse ECs.
Number of datasets analyzed across EC subtypes for each of the five indicated genes, n = 240. a, Stacked bar charts depicting the total number of datasets and the frequency at which transcripts for the indicated genes were detected (>0 TPM) or not detected (0 TPM), resolved by EC subtype (HUVEC n = 128, HDMEC n = 15, mouse lung EC n = 24, mouse brain EC n = 54, mouse retina EC n = 19). b, Transcript levels for the indicated genes with expression >0 TPM in each dataset for the indicated EC subtypes, including boxplots to illustrate the median (center line) and interquartile range (box limits) (for n, see the corresponding source data file); each data point represents one dataset. The red dashed line indicates the 1 TPM threshold, a commonly used albeit heuristic transcript level above which a gene is considered to be expressed at a level that may be biologically relevant.
