Extended Data Fig. 2: Atherosclerosis does not affect splenic stromal cells.
From: Hyperlipidemia-induced hematopoiesis is repressed by MLKL in endothelial cells of the splenic niche
Representative images and quantification of PDGFRβ+ area in the splenic red pulp after 4, 8 or 16 weeks of HCD feeding in Apoe-/- mice. PDGFRβ shown in green and nuclei in blue. Week 4: n = 2 mice, Weeks 8 & 16: n = 3 mice. Scale bar = 500μm. Quantification is represented as a percent of the red pulp area. WP: white pulp. Data are shown as mean ± s.e.m. Statistical significance was determined by one-way ANOVA followed by Holm-Sidak’s post-hoc test for multiple comparisons.
