Extended Data Fig. 5: Cardiomyocyte nucleation in CycleTrack-positive population after infarction and miR-199a treatment.
From: Genetic tracing and topography of spontaneous and stimulated cardiac regeneration in mice
Representative immunofluorescence images (b) and quantification (a,c) of the number of nuclei per GFP-negative and GFP-positive CMs isolated from the infarct border zone of Z/EG mice 30 days after LAD coronary artery ligation and injection with AAV9-CyB-Cre and either AAV9-Control or AAV9-miR-199a (n = 3 different animals; 30 to 60 cells per GFP-positive cells per animal, 90 to 110 GFP-negative cells per animal; one-way ANOVA with Tukey’s multiple comparisons). Data are displayed as mean±s.e.m. Scale bar: 20 μm.
